After graduating at the “Hochschule für Musik und Darstellende Kunst Frankfurt” as a Concert Pianist with studies in Conducting, Singing and Composing Uwe Berkemer started to work as a multitalented musician at a young age. Concerts, CD productions, radio and TV recordings regularly take him to the important culture metropolises of Germany, England, Ireland, Italy, Belgium, France, Spain, Switzerland, Austria, the USA, Canada, etc. 

In 2000 he married the extraordinary Georgian Violinist Bela Makharadze. Since then he has been performing many international concerts together with her.

Among his most important compositions are his sonata for Cello and Piano: WP Germany 1999, Violin Concerto: WP 2000 Germany, Fantasy for String Orchestra: WP 2001 Georgia, “Ilankugha”– a musical fairy tale for speaker, string orchestra and piano: WP 2001 Germany, Reflexionen für Cello: WP USA 2005, Chamber Symphony: WP France 2007, Marie`s guide to the orchestra: WP 2016 Germany etc. 

From 2000 to 2003 he was Principal Guest Conductor of the Georgian State Chamber Orchestra. 

Since 2001 he has been Principal Conductor and Artistic Director of the World Chamber Orchestra. 

In 2005 he founded the Caucasian Chamber Orchestra. 

In 2007 Uwe Berkemer was awarded the Certificate of Honour from the Minister of Culture of Armenia for his outstanding cultural engagement in the Caucasus region. 

In June 2007 a 90‐minute documentary movie “Grozny Dreaming” about the Orchestra and the vision of its conductor was shot for the International Cinema (World Premiere August 2008 in Ascona) and was awarded the first Prize of the International FilmFestival Verona‐ Lessinia (Lessinia d'oro '08). 

In 2008 he was nominated as the first “Ambassador of Utopia” by the Monte‐Verita Foundation Ascona in cooperation with the government of Venice. 

Since 2008 the Caucasian Chamber Orchestra has been working on temporary projects, as the orchestra’s common ground and financial basis in Tiflis has been destroyed by the war between Georgia and Russia. 

In March 2016 the Caucasian Chamber Orchestra celebrated a special JubileeTour according to its 10th anniversary.

In 2017 the first Festival “Youths for Classics in the Caucasus” took place in Tbilisi under the leadership of the Caucasian Chamber Orchestra and its Artistic Director Uwe Berkemer. 

In 2020 he established the first operafestival Ibbenbüren “SCHÜLER‐MACHEN‐OPER” and performed Mozart`s Opera “Die Zauberflöte” three times with the Caucasian Chamber Orchestra as orchestra in residence. 

In 2021 he was nominated as an Honorary Professor (Prof. h.c.) by the David Aghmashenebeli Academy Tbilisi.